2353409-75-1

2353409-75-1 structure
2353409-75-1 structure
  • Name: m-PEG8-ethoxycarbonyl-propanoic acid
  • Chemical Name: m-PEG8-ethoxycarbonyl-propanoic acid
  • CAS Number: 2353409-75-1
  • Molecular Formula: C21H40O12
  • Molecular Weight: 484.54
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:49:55
  • Modify Date: 2024-01-12 19:44:03
  • m-PEG8-ethoxycarbonyl-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG8-ethoxycarbonyl-propanoic acid
Description m-PEG8-ethoxycarbonyl-propanoic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C21H40O12
Molecular Weight 484.54