Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mal-amido-PEG12-acid
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: MAL-dPEG12-acid
Price: ￥Inquiry/10kg
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

2378428-27-2

2378428-27-2 structure

2378428-27-2 structure

Name: Mal-amido-PEG12-acid
Chemical Name: Mal-amido-PEG12-acid
CAS Number: 2378428-27-2
Molecular Formula: C₃₄H₆₀N₂O₁₇
Molecular Weight: 768.84
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:34:47
Modify Date: 2024-01-03 20:29:36
Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-amido-PEG12-acid

Description	Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₄H₆₀N₂O₁₇
Molecular Weight	768.84