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2112731-42-5

2112731-42-5 structure
2112731-42-5 structure
  • Name: Mal-amido-PEG7-acid
  • Chemical Name: Mal-amido-PEG7-acid
  • CAS Number: 2112731-42-5
  • Molecular Formula: C24H40N2O12
  • Molecular Weight: 548.58
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 14:40:05
  • Modify Date: 2024-01-13 22:58:07
  • Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amido-PEG7-acid
Synonyms MFCD30723255
Description Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C24H40N2O12
Molecular Weight 548.58