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2112731-43-6

2112731-43-6 structure
2112731-43-6 structure
  • Name: Mal-amido-PEG9-acid
  • Chemical Name: Mal-amido-PEG9-acid
  • CAS Number: 2112731-43-6
  • Molecular Formula: C28H48N2O14
  • Molecular Weight: 636.69
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 13:20:15
  • Modify Date: 2024-01-02 17:11:57
  • Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-amido-PEG9-acid
Synonyms MFCD30723254
Description Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C28H48N2O14
Molecular Weight 636.69