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1823885-81-9

1823885-81-9 structure
1823885-81-9 structure
  • Name: Mal-PEG1-Bromide
  • Chemical Name: Mal-PEG1-bromide
  • CAS Number: 1823885-81-9
  • Molecular Formula: C8H10BrNO3
  • Molecular Weight: 248.07
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:11:03
  • Modify Date: 2024-01-10 20:15:59
  • Mal-PEG1-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG1-bromide
Description Mal-PEG1-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H10BrNO3
Molecular Weight 248.07