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660843-22-1

660843-22-1 structure
660843-22-1 structure
  • Name: Mal-PEG2-amine TFA
  • Chemical Name: Mal-PEG2-NH2
  • CAS Number: 660843-22-1
  • Molecular Formula: C10H16N2O4
  • Molecular Weight: 228.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 23:05:49
  • Modify Date: 2024-01-08 13:30:08
  • Mal-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Mal-PEG2-NH2
Description Mal-PEG2-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C10H16N2O4
Molecular Weight 228.25