2250216-91-0

2250216-91-0 structure

2250216-91-0 structure

Name: tert-Butyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oate
Chemical Name: Mal-PEG5-Boc
CAS Number: 2250216-91-0
Molecular Formula: C₂₁H₃₅NO₉
Molecular Weight: 445.50
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 00:44:07
Modify Date: 2024-01-05 11:27:57
Mal-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG5-Boc

Description	Mal-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₁H₃₅NO₉
Molecular Weight	445.50