2322322-23-4

2322322-23-4 structure

2322322-23-4 structure

Name: N-(4-(6-Methyl-1,2,4,5-tetrazin-3-yl)benzyl)-4,7,10,13,16-pentaoxanonadec-18-ynamide
Chemical Name: Methyltetrazine-amido-PEG5-alkyne
CAS Number: 2322322-23-4
Molecular Formula: C₂₄H₃₃N₅O₆
Molecular Weight: 487.55
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 12:08:31
Modify Date: 2024-04-03 12:20:04
Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-amido-PEG5-alkyne
Synonyms	MFCD31811434

Description	Methyltetrazine-amido-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₄H₃₃N₅O₆
Molecular Weight	487.55

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