2183440-34-6

2183440-34-6 structure
2183440-34-6 structure
  • Name: Methyltetrazine-PEG8-NHS ester
  • Chemical Name: Methyltetrazine-PEG8-NHS ester
  • CAS Number: 2183440-34-6
  • Molecular Formula: C32H47N5O13
  • Molecular Weight: 709.74
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 10:47:20
  • Modify Date: 2024-01-17 21:04:43
  • Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyltetrazine-PEG8-NHS ester
Description Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C32H47N5O13
Molecular Weight 709.74