2112731-51-6

2112731-51-6 structure

2112731-51-6 structure

Name: N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
Chemical Name: N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
CAS Number: 2112731-51-6
Molecular Formula: C₂₆H₄₅N₅O₁₂
Molecular Weight: 619.66
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 17:47:20
Modify Date: 2024-01-10 07:45:12
N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Azido-PEG3)-N-Boc-PEG3-NHS ester

Description	N-(Azido-PEG3)-N-Boc-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₄₅N₅O₁₂
Molecular Weight	619.66