2100306-72-5

2100306-72-5 structure
2100306-72-5 structure
  • Name: N-(Azido-PEG3)-N-Fluorescein-PEG4-acid
  • Chemical Name: N-(Azido-PEG3)-N-Fluorescein-PEG4-acid
  • CAS Number: 2100306-72-5
  • Molecular Formula: C40H49N5O14S
  • Molecular Weight: 855.91
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:16:31
  • Modify Date: 2024-01-09 12:41:47
  • N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-(Azido-PEG3)-N-Fluorescein-PEG4-acid
Description N-(Azido-PEG3)-N-Fluorescein-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C40H49N5O14S
Molecular Weight 855.91