2093153-08-1

2093153-08-1 structure
2093153-08-1 structure
  • Name: N-Boc-N-bis(PEG4-NHS ester)
  • Chemical Name: N-Boc-N-bis(PEG4-NHS ester)
  • CAS Number: 2093153-08-1
  • Molecular Formula: C35H57N3O18
  • Molecular Weight: 807.84
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:37:06
  • Modify Date: 2024-01-15 11:32:29
  • N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name N-Boc-N-bis(PEG4-NHS ester)
Synonyms MFCD29912670
Description N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C35H57N3O18
Molecular Weight 807.84