2110449-00-6

2110449-00-6 structure

2110449-00-6 structure

Name: N-DBCO-N-bis(PEG2-C2-acid)
Chemical Name: N-DBCO-N-bis(PEG2-C2-acid)
CAS Number: 2110449-00-6
Molecular Formula: C₃₃H₄₀N₂O₁₀
Molecular Weight: 624.68
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:44:39
Modify Date: 2024-01-11 09:36:04
N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-DBCO-N-bis(PEG2-C2-acid)

Description	N-DBCO-N-bis(PEG2-C2-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₃H₄₀N₂O₁₀
Molecular Weight	624.68