2107273-08-3

2107273-08-3 structure

2107273-08-3 structure

Name: N,N'-bis-(propargyl-PEG4)-Cy5 (chloride)
Chemical Name: N,N'-bis-(propargyl-PEG4)-Cy5
CAS Number: 2107273-08-3
Molecular Formula: C₄₇H₆₃ClN₂O₈
Molecular Weight: 819.46
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 15:01:04
Modify Date: 2024-01-02 12:48:12
N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N,N'-bis-(propargyl-PEG4)-Cy5

Description	N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₇H₆₃ClN₂O₈
Molecular Weight	819.46