2112737-74-1

2112737-74-1 structure

2112737-74-1 structure

Name: N-(Tos-peg4)-n-bis(peg4-t-butyl ester)
Chemical Name: N-(Tos-PEG4)-N-bis(PEG4-Boc)
CAS Number: 2112737-74-1
Molecular Formula: C₄₅H₈₁NO₁₈S
Molecular Weight: 956.19
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:37:09
Modify Date: 2024-01-10 20:38:16
N-(Tos-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	N-(Tos-PEG4)-N-bis(PEG4-Boc)
Synonyms	MFCD30828699

Description	N-(Tos-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₄₅H₈₁NO₁₈S
Molecular Weight	956.19