2100306-81-6

2100306-81-6 structure
2100306-81-6 structure
  • Name: NH-bis(PEG1-azide)
  • Chemical Name: NH-bis(C2-PEG1-azide)
  • CAS Number: 2100306-81-6
  • Molecular Formula: C8H17N7O2
  • Molecular Weight: 243.27
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:53:41
  • Modify Date: 2024-01-09 17:01:55
  • NH-bis(C2-PEG1-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(C2-PEG1-azide)
Description NH-bis(C2-PEG1-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H17N7O2
Molecular Weight 243.27