2182601-69-8

2182601-69-8 structure
2182601-69-8 structure
  • Name: NH-bis(PEG2-Boc)
  • Chemical Name: NH-bis(C2-PEG2-NH-Boc)
  • CAS Number: 2182601-69-8
  • Molecular Formula: C22H45N3O8
  • Molecular Weight: 479.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:05:04
  • Modify Date: 2024-01-20 13:26:24
  • NH-bis(C2-PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name NH-bis(C2-PEG2-NH-Boc)
Synonyms MFCD31536767
Description NH-bis(C2-PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H45N3O8
Molecular Weight 479.61