Shanghai Nianxing Industrial Co., Ltd
China
Product Name: NPS ALX Compound 4a dihydrochloride
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: NPS ALX Compound 4a dihydrochloride
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

1781934-44-8

1781934-44-8 structure

1781934-44-8 structure

Name: NPS ALX Compound 4a dihydrochloride
Chemical Name: NPS ALX Compound 4a dihydrochloride
CAS Number: 1781934-44-8
Molecular Formula: C₂₅H₂₇Cl₂N₃O₂S
Molecular Weight: 504.47
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2020-06-01 20:23:14
Modify Date: 2025-08-26 13:19:51
NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM and a Ki of 0.2 nM[1].

Name	NPS ALX Compound 4a dihydrochloride

Description	NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM and a Ki of 0.2 nM[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT6 Receptor:7.2 nM (IC50) 5-HT6 Receptor:0.2 nM (Ki)
References	[1]. Isaac M, et al. 6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindolesderivatives as novel, potent, and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21.

Molecular Formula	C₂₅H₂₇Cl₂N₃O₂S
Molecular Weight	504.47

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