2055736-28-0

2055736-28-0 structure
2055736-28-0 structure
  • Name: PC Methyltetrazine-PEG4-NHS carbonate ester
  • Chemical Name: PC Methyltetrazine-PEG4-NHS carbonate ester
  • CAS Number: 2055736-28-0
  • Molecular Formula: C35H43N7O14
  • Molecular Weight: 785.75
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 19:21:41
  • Modify Date: 2024-01-09 10:36:00
  • PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name PC Methyltetrazine-PEG4-NHS carbonate ester
Description PC Methyltetrazine-PEG4-NHS carbonate ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C35H43N7O14
Molecular Weight 785.75