2086689-09-8

2086689-09-8 structure

2086689-09-8 structure

Name: Propargyl-PEG3-methyl ester
Chemical Name: Propargyl-PEG3-methyl ester
CAS Number: 2086689-09-8
Molecular Formula: C₁₁H₁₈O₅
Molecular Weight: 230.26
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 07:11:27
Modify Date: 2024-01-12 14:38:32
Propargyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG3-methyl ester

Description	Propargyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₁H₁₈O₅
Molecular Weight	230.26