1412905-18-0

1412905-18-0 structure

1412905-18-0 structure

Name: Propargyl-PEG3-SH
Chemical Name: Propargyl-PEG3-SH
CAS Number: 1412905-18-0
Molecular Formula: C₉H₁₆O₃S
Molecular Weight: 204.29
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:10:04
Modify Date: 2024-01-09 12:50:15
Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG3-SH

Description	Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₉H₁₆O₃S
Molecular Weight	204.29