1872433-74-3

1872433-74-3 structure
1872433-74-3 structure
  • Name: Propargyl-PEG4-(CH2)3-acid
  • Chemical Name: Propargyl-PEG4-CH2-acid
  • CAS Number: 1872433-74-3
  • Molecular Formula: C13H22O6
  • Molecular Weight: 274.31
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 17:07:37
  • Modify Date: 2024-01-09 20:44:09
  • Propargyl-PEG4-CH2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG4-CH2-acid
Synonyms MFCD29079388
Description Propargyl-PEG4-CH2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C13H22O6
Molecular Weight 274.31