2055024-43-4

2055024-43-4 structure

2055024-43-4 structure

Name: Propargyl-peg4-sulfone-peg4-t-butyl ester
Chemical Name: Propargyl-PEG4-Sulfone-PEG4-Boc
CAS Number: 2055024-43-4
Molecular Formula: C₂₆H₄₈O₁₂S
Molecular Weight: 584.72
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 00:14:53
Modify Date: 2024-01-05 09:53:19
Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG4-Sulfone-PEG4-Boc
Synonyms	MFCD30182061

Description	Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₄₈O₁₂S
Molecular Weight	584.72