2055024-43-4

2055024-43-4 structure
2055024-43-4 structure
  • Name: Propargyl-peg4-sulfone-peg4-t-butyl ester
  • Chemical Name: Propargyl-PEG4-Sulfone-PEG4-Boc
  • CAS Number: 2055024-43-4
  • Molecular Formula: C26H48O12S
  • Molecular Weight: 584.72
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 00:14:53
  • Modify Date: 2024-01-05 09:53:19
  • Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG4-Sulfone-PEG4-Boc
Synonyms MFCD30182061
Description Propargyl-PEG4-Sulfone-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C26H48O12S
Molecular Weight 584.72