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1817735-29-7

1817735-29-7 structure
1817735-29-7 structure
  • Name: Propargyl-PEG4-sulfonic acid
  • Chemical Name: Propargyl-PEG4-sulfonic acid
  • CAS Number: 1817735-29-7
  • Molecular Formula: C11H20O7S
  • Molecular Weight: 296.34
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 21:59:10
  • Modify Date: 2024-01-09 16:46:28
  • Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG4-sulfonic acid
Synonyms MFCD29042379
Description Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H20O7S
Molecular Weight 296.34