2098621-90-8
2098621-90-8 structure
- Name: Protein kinase affinity probe 1
- Chemical Name: Protein kinase affinity probe 1
- CAS Number: 2098621-90-8
- Molecular Formula: C26H39ClN8O2
- Molecular Weight: 531.09
- Catalog: Research Areas Others
- Create Date: 2020-06-01 14:47:44
- Modify Date: 2025-08-26 16:53:58
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Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3)[1].
| Name | Protein kinase affinity probe 1 |
|---|
| Description | Protein kinase affinity probe 1 is a novel protein kinase affinity probe for the functional identification of protein kinases (PKs). Protein kinase affinity probe 1 is a modified Purvalanol B (HY-18299) probe with 50% beads loading (Compound S3)[1]. |
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| Related Catalog | |
| In Vitro | “S” indicates that the PKI (Purvalanol B) is sepharose-bound[1]. In a series of pull-down experiments from the lysates of HeLa cells, the effects of 0.1, 0.5, 1, 2, 5, 10, 25, and 50% loadings of PK inhibitors is determined. Examine higher bead loadings (75 and 100%) are prevented due to lack of compound solubility and poor reproducibility of the synthesis outcomes. 50% loading is the highest feasible in this study[1]. |
| References |
| Molecular Formula | C26H39ClN8O2 |
|---|---|
| Molecular Weight | 531.09 |