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1817735-36-6

1817735-36-6 structure
1817735-36-6 structure
  • Name: Pyrene-PEG3-azide
  • Chemical Name: Pyrene-amido-PEG4-azide
  • CAS Number: 1817735-36-6
  • Molecular Formula: C25H28N4O4
  • Molecular Weight: 448.51
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:11:55
  • Modify Date: 2024-01-10 23:22:49
  • Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Pyrene-amido-PEG4-azide
Description Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C25H28N4O4
Molecular Weight 448.51
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