110351-91-2
110351-91-2 structure
- Name: (R)-Exatecan Intermediate 1
- Chemical Name: 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine
- CAS Number: 110351-91-2
- Molecular Formula: C13H13NO5
- Molecular Weight: 263.25
- Catalog: Research Areas Cancer
- Create Date: 2017-04-24 17:54:09
- Modify Date: 2025-08-24 20:54:29
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(R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2].
| Name | 5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f]Δ6,8-tetrahydroindolizine |
|---|---|
| Synonyms |
(4R)-4-ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
.5'(R)-1,5-dioxo-5'-ethyl-5'-hydroxy-2'H,5'H,6'H-6'-oxopyrano[3',4'-f] |
| Description | (R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1 (HY-42487). Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631), a camptothecin-based anticancer agent. Exatecan inhibits tumor growth by interfering with the proliferation and division of tumor cells by interacting with DNA. Exatecan is primarily used in research into a variety of cancers including ovarian, lung and breast cancer[1][2]. |
|---|---|
| Related Catalog |
| Molecular Formula | C13H13NO5 |
|---|---|
| Molecular Weight | 263.25 |
| Exact Mass | 263.07900 |
| PSA | 85.60000 |
| LogP | 0.08910 |
| Precursor 0 | |
|---|---|
| DownStream 1 | |
