2226611-29-4

2226611-29-4 structure

2226611-29-4 structure

Name: tert-Butyl ((23-amino-3,6,9,12,15,18,21-heptaoxatricosyl)oxy)carbamate
Chemical Name: t-Boc-Aminooxy-PEG7-amine
CAS Number: 2226611-29-4
Molecular Formula: C₂₁H₄₄N₂O₁₀
Molecular Weight: 484.58
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 18:37:44
Modify Date: 2024-07-17 22:05:15
t-Boc-Aminooxy-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	t-Boc-Aminooxy-PEG7-amine

Description	t-Boc-Aminooxy-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₁H₄₄N₂O₁₀
Molecular Weight	484.58