2250217-32-2

2250217-32-2 structure

2250217-32-2 structure

Name: TCO-PEG3-triethoxysilane
Chemical Name: TCO-PEG3-amide-C3-triethoxysilane
CAS Number: 2250217-32-2
Molecular Formula: C₂₇H₅₂N₂O₉Si
Molecular Weight: 576.80
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 22:44:09
Modify Date: 2024-01-10 09:10:13
TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	TCO-PEG3-amide-C3-triethoxysilane
Synonyms	MFCD31811541

Description	TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₇H₅₂N₂O₉Si
Molecular Weight	576.80