2250217-32-2

2250217-32-2 structure
2250217-32-2 structure
  • Name: TCO-PEG3-triethoxysilane
  • Chemical Name: TCO-PEG3-amide-C3-triethoxysilane
  • CAS Number: 2250217-32-2
  • Molecular Formula: C27H52N2O9Si
  • Molecular Weight: 576.80
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 22:44:09
  • Modify Date: 2024-01-10 09:10:13
  • TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name TCO-PEG3-amide-C3-triethoxysilane
Synonyms MFCD31811541
Description TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C27H52N2O9Si
Molecular Weight 576.80