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1239588-09-0

1239588-09-0 structure
1239588-09-0 structure
  • Name: Tos-PEG4-methyl ester
  • Chemical Name: Tos-PEG3-C2-methyl ester
  • CAS Number: 1239588-09-0
  • Molecular Formula: C17H26O8S
  • Molecular Weight: 390.45
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 20:28:02
  • Modify Date: 2024-01-12 19:05:35
  • Tos-PEG3-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Tos-PEG3-C2-methyl ester
Synonyms MFCD28967602
Description Tos-PEG3-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C17H26O8S
Molecular Weight 390.45