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1949793-62-7

1949793-62-7 structure
1949793-62-7 structure
  • Name: Tos-PEG6-CH2CO2tBu
  • Chemical Name: Tos-PEG5-CH2COOtBu
  • CAS Number: 1949793-62-7
  • Molecular Formula: C23H38O10S
  • Molecular Weight: 506.61
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 18:13:34
  • Modify Date: 2024-01-13 18:12:21
  • Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Tos-PEG5-CH2COOtBu
Synonyms MFCD30828689
Description Tos-PEG5-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H38O10S
Molecular Weight 506.61