159858-33-0

159858-33-0 structure

159858-33-0 structure

Name: (S)-2-((S)-2-amino-3-methylbutanamido)-5-ureidopentanoic acid
Chemical Name: Val-Cit
CAS Number: 159858-33-0
Molecular Formula: C₁₁H₂₂N₄O₄
Molecular Weight: 274.32
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2020-06-01 23:24:34
Modify Date: 2024-01-04 23:28:45
Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Val-Cit

Description	Val-Cit is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula	C₁₁H₂₂N₄O₄
Molecular Weight	274.32