Shanghai Nianxing Industrial Co., Ltd
China
Product Name: BigLEN(rat)
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: BigLEN(rat)
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

369377-66-2

369377-66-2 structure

369377-66-2 structure

Name: BigLEN(rat) TFA
Chemical Name: BigLEN(rat)
CAS Number: 369377-66-2
Molecular Formula: C₇₆H₁₂₈N₂₄O₂₃
Molecular Weight: 1745.98
Catalog: Research Areas Neurological Disease
Create Date: 2020-08-11 09:06:26
Modify Date: 2024-01-10 15:25:34
BigLEN(rat), one of the most abundant peptides in brain, is a potent GPR171 agonist, with an EC50 of 1.6 nM[1][2].

Name	BigLEN(rat)

Description	BigLEN(rat), one of the most abundant peptides in brain, is a potent GPR171 agonist, with an EC50 of 1.6 nM[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	BigLEN-GPR171 system plays an important role in regulating feeding and metabolism in mice[1][2].
References	[1]. Seshat M Mack, et al. Neuropeptide PEN and Its Receptor GPR83: Distribution, Signaling, and Regulation. ACS Chem Neurosci. 2019 Apr 17;10(4):1884-1891. [2]. Ivone Gomes, et al. GPR171 Is a Hypothalamic G Protein-Coupled Receptor for BigLEN, a Neuropeptide Involved in Feeding. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16211-6.

Molecular Formula	C₇₆H₁₂₈N₂₄O₂₃
Molecular Weight	1745.98

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