675135-69-0

675135-69-0 structure

675135-69-0 structure

Name: CXCR4 antagonist 1
Chemical Name: CXCR4 antagonist 1
CAS Number: 675135-69-0
Molecular Formula: C₂₇H₄₃N₇
Molecular Weight: 465.68
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2020-08-08 16:20:41
Modify Date: 2024-01-05 07:54:36
CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity[1].

Name	CXCR4 antagonist 1

Description	CXCR4 antagonist 1 is a potent CXCR4 antagonist. CXCR4 antagonist 1 has anti-HIV activity[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> GPCR/G Protein >> CXCR Signaling Pathways >> Immunology/Inflammation >> CXCR
Target	CXCR4 HIV
In Vitro	HIV-1 entry is triggered by interaction of gp120 with CD4 and chemokine receptors (CKRs), such as CCR5 and CXCR4[1].
References	[1]. Yuta Hikichi, et al. Increased HIV-1 Sensitivity to Neutralizing Antibodies by Mutations in the Env V3-coding Region for Resistance to CXCR4 Antagonists. J Gen Virol. 2016 Sep;97(9):2427-2440.

Molecular Formula	C₂₇H₄₃N₇
Molecular Weight	465.68