1416983-77-1

1416983-77-1 structure

Name: MSG 606
Chemical Name: MSG606
CAS Number: 1416983-77-1
Molecular Formula: C₆₂H₈₂N₂₀O₁₃S
Molecular Weight: 1347.51
Catalog: Signaling Pathways GPCR/G Protein Melanocortin Receptor
Create Date: 2020-08-09 18:24:36
Modify Date: 2024-01-30 19:50:28
MSG606 is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 exhibits binding affinity for A375 melanoma cells in vitro. MSG606 reverses morphine-induced hyperalgesia in female mice, with no effect in male mice.

Name	MSG606

Description	MSG606 is a potent human MC1 receptor antagonist (IC50=17 nM). MSG606 also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). MSG606 exhibits binding affinity for A375 melanoma cells in vitro. MSG606 reverses morphine-induced hyperalgesia in female mice, with no effect in male mice.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

Molecular Formula	C₆₂H₈₂N₂₀O₁₃S
Molecular Weight	1347.51