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1379577-47-5

1379577-47-5 structure
1379577-47-5 structure
  • Name: Puwainaphycin F
  • Chemical Name: Puwainaphycin F
  • CAS Number: 1379577-47-5
  • Molecular Formula: C53H87N13O15
  • Molecular Weight: 1146.34
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
  • Create Date: 2020-08-07 18:42:40
  • Modify Date: 2024-01-11 16:54:02
  • Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].

Name Puwainaphycin F
Description Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].
Related Catalog
In Vitro Puwainaphycin F has an IC50 of 2.19 μM in HeLa cells[1].
References

[1]. Pavel Hrouzek , et al. The cyanobacterial cyclic lipopeptides puwainaphycins F/G are inducing necrosis via cell membrane permeabilization and subsequent unusual actin relocalization. Chem Res Toxicol. 2012 Jun 18;25(6):1203-11.

Molecular Formula C53H87N13O15
Molecular Weight 1146.34