2127150-20-1

2127150-20-1 structure
2127150-20-1 structure
  • Name: JF669, SE
  • Chemical Name: JF669, SE
  • CAS Number: 2127150-20-1
  • Molecular Formula: C34H30F3N3O6SSi
  • Molecular Weight: 693.76
  • Catalog: Research Areas Others
  • Create Date: 2021-11-13 10:35:48
  • Modify Date: 2024-01-12 10:40:29
  • JF669, SE, a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669−HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1].

Name JF669, SE
Description JF669, SE, a red fluorescent dye, can be directly reacted with the available thiol-containing HaloTag ligand under mild conditions (DIEA, DMF) to afford a JF669−HaloTag ligand in a single step (Ex = 669 nm; Em = 682 nm)[1].
Related Catalog
In Vitro JF669 undergoes rapid conversion to thioether product (<5 min to completion) in organic solvents, where the dye predominantly adopts the closed form[1]. JF669 displays comparatively excellent photostability, retaining 97% fluorescence after the same number of cycles[1].
References

[1]. Jonathan B Grimm, et al. General Synthetic Method for Si-Fluoresceins and Si-Rhodamines. ACS Cent Sci. 2017 Sep 27;3(9):975-985.

Molecular Formula C34H30F3N3O6SSi
Molecular Weight 693.76
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