2225940-51-0

2225940-51-0 structure

Name: Pomalidomide-C7-COOH
Chemical Name: Pomalidomide-C7-COOH
CAS Number: 2225940-51-0
Molecular Formula: C₂₁H₂₅N₃O₆
Molecular Weight: 415.44
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2020-11-28 16:32:43
Modify Date: 2024-01-10 11:44:23
Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].

Name	Pomalidomide-C7-COOH

Description	Pomalidomide-C7-COOH is a synthesized E3 ligase cereblon ligand-linker conjugate. Pomalidomide-C7-COOH is an intermediate for the synthesis of PROTAC BCL-XL degraders[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Target	Cereblon[1]
References	[1]. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.