911378-38-6

911378-38-6 structure

Name: RBI-257 Maleate
Chemical Name: RBI 257 (maleate)
CAS Number: 911378-38-6
Molecular Formula: C₂₅H₃₂IN₃O₅
Molecular Weight: 581.44
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2021-01-09 19:39:53
Modify Date: 2024-01-19 11:44:25
RBI-257 maleate is a potent dopamine D4 receptor antagonist with a Ki value of 0.3 nM[1].

Name	RBI 257 (maleate)
Synonyms	2-Pyridinamine, N-[1-[(4-iodophenyl)methyl]-4-piperidinyl]-N-methyl-3-(1-methylethoxy)-, (2Z)-2-butenedioate (1:1) N-[1-(4-Iodobenzyl)-4-piperidinyl]-3-isopropoxy-N-methyl-2-pyridinamine (2Z)-2-butenedioate (1:1) RBI 257 (maleate)

Description	RBI-257 maleate is a potent dopamine D4 receptor antagonist with a Ki value of 0.3 nM[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Wilke RA, et, al. Dopamine D4 receptor mediated inhibition of potassium current in neurohypophysial nerve terminals. J Pharmacol Exp Ther. 1998 Feb;284(2):542-8.