Name | ML-179 |
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Synonyms |
2,4(1H,3H)-Pyrimidinedione, 3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-
3-Cyclohexyl-6-{4-[3-(trifluoromethyl)phenyl]-1-piperazinyl}-2,4(1H,3H)-pyrimidinedione 3-cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]-1H-pyrimidine-2,4-dione ML-179 |
Description | ML179 (SR-1309) is a inverse LRH1 (Liver receptor homologue-1) agonist with IC50 of 320 nM. ML179 shows anti-proliferation activity in MDA-MB-231 cells. ML179 has the potential for the research of ER-negative breast cancer[1]. |
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Related Catalog | |
Target |
LRH-1[1] |
References |
Density | 1.3±0.1 g/cm3 |
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Molecular Formula | C21H25F3N4O2 |
Molecular Weight | 422.44 |
Exact Mass | 422.192963 |
LogP | 4.80 |
Index of Refraction | 1.568 |