1217448-19-5

1217448-19-5 structure

Name: Galnon (trifluoroacetate salt)
Chemical Name: Galnon (trifluoroacetate salt)
CAS Number: 1217448-19-5
Molecular Formula: C₄₂H₄₇F₃N₄O₈
Molecular Weight: 792.840
Catalog: Signaling Pathways GPCR/G Protein Neuropeptide Y Receptor
Create Date: 2021-06-03 14:45:56
Modify Date: 2024-01-12 19:55:39
Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects[1][2].

Name	Galnon (trifluoroacetate salt)
Synonyms	3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-lysinamide trifluoroacetate (1:1) Galnon (trifluoroacetate salt) 7-((9-Fluorenylmethoxycarbonyl)cyclohexylalanyllysyl) amino-4-methylcoumarin trifluoroacetate salt MFCD06798339 Galnon trifluoroacetate salt Acetic acid, 2,2,2-trifluoro-, compd. with L-lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- (1:1)

Description	Galnon TFA is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon TFA exhibits anticonvulsant and anxiolytic effects[1][2].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor
References	[1]. Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. [2]. Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20.