1329496-63-0

1329496-63-0 structure

Name: Maprotiline-d3 (hydrochloride)
Chemical Name: Maprotiline-d3 (hydrochloride)
CAS Number: 1329496-63-0
Molecular Formula: C₂₀H₂₁D₃ClN
Molecular Weight: 316.88
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2021-06-11 18:30:22
Modify Date: 2024-01-19 22:49:09
Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride).

Name	Maprotiline-d3 (hydrochloride)
Synonyms	9,10-Ethanoanthracene-9(10H)-propanamine, N-(methyl-d3)-, hydrochloride (1:1) N-(2H3)Methyl-3-(tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaen-1-yl)-1-propanamine hydrochloride (1:1)

Description	Maprotiline-d3 (hydrochloride) is deuterium labeled Maprotiline (hydrochloride).
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Peng, W.H., et al., Berberine produces antidepressant-like effects in the forced swim test and in the tail suspension test in mice. Life Sci, 2007. 81(11): p. 933-8. [3]. http://en.wikipedia.org/wiki/Maprotiline