2148296-00-6

2148296-00-6 structure
2148296-00-6 structure
  • Name: Benzyl-PEG6-t-butyl ester
  • Chemical Name: Benzyl-PEG6-t-butyl ester
  • CAS Number: 2148296-00-6
  • Molecular Formula: C24H40O8
  • Molecular Weight: 456.57
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-05-28 18:20:42
  • Modify Date: 2024-01-09 12:25:12
  • Benzyl-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Benzyl-PEG6-t-butyl ester
Description Benzyl-PEG6-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C24H40O8
Molecular Weight 456.57