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2148295-98-9

2148295-98-9 structure
2148295-98-9 structure
  • Name: Bromo-PEG4-NHS ester
  • Chemical Name: Bromo-PEG4-NHS ester
  • CAS Number: 2148295-98-9
  • Molecular Formula: C15H24BrNO8
  • Molecular Weight: 426.26
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-27 17:44:39
  • Modify Date: 2024-01-10 20:21:50
  • Bromo-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG4-NHS ester
Description Bromo-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C15H24BrNO8
Molecular Weight 426.26