190714-28-4

190714-28-4 structure
190714-28-4 structure
  • Name: ICG-Sulfo-OSu sodium
  • Chemical Name: ICG-Sulfo-OSu sodium
  • CAS Number: 190714-28-4
  • Molecular Formula: C49H52N3NaO10S2
  • Molecular Weight: 930.07
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 18:43:12
  • Modify Date: 2024-01-06 10:02:00
  • ICG-Sulfo-OSu sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name ICG-Sulfo-OSu sodium
Description ICG-Sulfo-OSu sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C49H52N3NaO10S2
Molecular Weight 930.07
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