1431957-72-0

1431957-72-0 structure
1431957-72-0 structure
  • Name: IYPTNGYTR
  • Chemical Name: IYPTNGYTR
  • CAS Number: 1431957-72-0
  • Molecular Formula: C49H73N13O15
  • Molecular Weight: 1084.18
  • Catalog: Research Areas Others
  • Create Date: 2021-09-10 19:58:30
  • Modify Date: 2025-12-29 18:32:00
  • IYPTNGYTR, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR can be used to monitor in vivo Trastuzumab metabolism[1].

Name IYPTNGYTR
Description IYPTNGYTR, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR can be used to monitor in vivo Trastuzumab metabolism[1].
Related Catalog
In Vitro IYPTNGYTR is deamidated at pH 7.5 and above, with a higher deamidation rate when the pH increases[1].
References

[1]. Bults P, et, al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016 Feb 2;88(3):1871-7.

Molecular Formula C49H73N13O15
Molecular Weight 1084.18
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