1284417-66-8

1284417-66-8 structure
1284417-66-8 structure
  • Name: m-PEG2-amido-Ph-NH2
  • Chemical Name: m-PEG2-amido-Ph-NH2
  • CAS Number: 1284417-66-8
  • Molecular Formula: C12H18N2O3
  • Molecular Weight: 238.28
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-06-07 20:37:17
  • Modify Date: 2024-01-09 00:06:28
  • m-PEG2-amido-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG2-amido-Ph-NH2
Description m-PEG2-amido-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H18N2O3
Molecular Weight 238.28