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58349-37-4

58349-37-4 structure
58349-37-4 structure
  • Name: Methyl acetate-PEG1
  • Chemical Name: Methyl acetate-PEG1
  • CAS Number: 58349-37-4
  • Molecular Formula: C5H10O4
  • Molecular Weight: 134.13
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-10 18:19:43
  • Modify Date: 2024-01-04 11:05:02
  • Methyl acetate-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyl acetate-PEG1
Synonyms MFCD10693398
Description Methyl acetate-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C5H10O4
Molecular Weight 134.13