1457940-75-8

1457940-75-8 structure

Name: Orexin receptor antagonist 2
Chemical Name: Orexin receptor antagonist 2
CAS Number: 1457940-75-8
Molecular Formula: C₂₅H₃₁N₅O₂
Molecular Weight: 433.55
Catalog: Signaling Pathways GPCR/G Protein Orexin Receptor (OX Receptor)
Create Date: 2021-05-20 02:41:42
Modify Date: 2025-08-26 19:08:24
Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].

Name	Orexin receptor antagonist 2

Description	Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor) Research Areas >> Neurological Disease
References	[1]. Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia. J Med Chem. 2013;56(19):7590-7607.

Molecular Formula	C₂₅H₃₁N₅O₂
Molecular Weight	433.55