1287660-82-5

1287660-82-5 structure
1287660-82-5 structure
  • Name: Propargyl-PEG2-bromide
  • Chemical Name: Propargyl-PEG2-bromide
  • CAS Number: 1287660-82-5
  • Molecular Formula: C7H11BrO2
  • Molecular Weight: 207.07
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-09-11 10:39:00
  • Modify Date: 2024-01-20 17:04:32
  • Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Propargyl-PEG2-bromide
Synonyms MFCD24465329
Description Propargyl-PEG2-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C7H11BrO2
Molecular Weight 207.07